MATERIAL and METHODS:
The study population consisted of 100 adult patients aged ≥ 18 years
with isolated severe MS in sinus rhythm recruited from Cardiology
Outpatient Department of our Tertiary care hospital between January 2019
and July 2020.
Patients with any of the following were excluded from the study:
- Concomitant mitral regurgitation (more than mild)
- Concomitant aortic stenosis and/or regurgitation (more than mild)
- History of mitral commisurotomy or valvuloplasty
- Associated congenital heart disease
- Left ventricular systolic dysfunction (ejection fraction <
50%)
- Associated diabetes mellitus, hypertension, chronic kidney disease or
coronary artery disease.
- Associated pregnancy
- Currently on oral anticoagulants or antiplatelet drugs
- Poor ECHO window
The study was approved by the institutional ethical committee and
written informed consent was taken from all the subjects. An initial
screening transthoracic echocardiography (TTE) was done and patients
meeting our inclusion/ exclusion criteria were given an appointment
for undergoing both TTE and TEE.